ISRAEL
Israel BioImaging
The EUBI-Israel Node is a multi-sited, multi-modal Node including seven hosting sites across Israel. It offers access to a broad range of technologies from biological, molecular to medical imaging. The focus and unique aspect of Israel Bioimaging is facilitating and enabling cross-modality imaging spanning all scales from single-molecule to in vivo and clinical imaging. The node enables seamless correlative imaging from Electron microscopy and advanced Biological microscopy through advanced live and high throughput imaging to in vivo preclinical and clinical imaging along with the capacity for advanced image analysis and computation.
Specialties and expertise of the Node
Israel BioImaging offers cutting edge imaging platforms and cross modality capabilities to allow multiscale imaging to enable seamless transition from cells to tissues and organs to whole body imaging. Applications range across all life forms and pathologies, from marine biology and plant science to developmental biology, infectious diseases, neuroscience, cancer and aging.
Offered Technologies
| Technologies | Euro-BioImaging |
| Deconvolution widefield microscopy (DWM) | ✓ |
| Laser scanning confocal microscopy (LSCM/CLSM) | ✓ |
| Spinning disk confocal microscopy (SDCM) | ✓ |
| Total internal reflection fluorescence microscopy (TIRF) | ✓ |
| Two-photon microscopy (2P) | ✓ |
| Single Molecula localisation microscopy (SMLM) | ✓ |
| Stimulated emission depletion microscopy (STED) | ✓ |
| Light-sheet mesoscopic imaging (SPIM or dSLSM) | ✓ |
| High throughput microscopy/high content screening (HTM/HCS) | ✓ |
| Fluorescence (cross)-correlation spectroscopy (FCS/FCCS) | ✓ |
| Fluorescence Resonance Energy Transfer (FRET) | ✓ |
| Fluorescence Recovery After Photobleaching (FRAP) | ✓ |
| Fluorescence Lifetime Imaging Microscopy (FLIM) | ✓ |
| TEM of chemical fixed samples (TEM) | ✓ |
| TEM of cryo-immobilized samples (TEM cryo samples)* | ✓ |
| EM tomography (ET) | ✓ |
| serial section TEM | ✓ |
| Serial Blockface SEM | ✓ |
| Immuno-gold EM on thawed cryo-sections (Tokuyasu-EM) | ✓ |
| Cryo Transmission Electron Microscopy (Cryo-TEM)* | ✓ |
| Cryo Scanning Electron Microscopy (Cryo-SEM)* | ✓ |
| pre-embed CLEM | ✓ |
| in-section CLEM | ✓ |
| Scanning Electron Microscopy (SEM) | ✓ |
| Elemental analysis * | ✓ |
| micro-MRI/MRS (Field >= 7 T) (HF) | ✓ |
| micro-CT | ✓ |
| micro-US | ✓ |
| in vivo optical imaging (OI) | ✓ |
| PhotoAcoustic Imaging (PAI) - med | ✓ |
| micro-PET/CT | ✓ |
| Intravital microscopy (IVM) - Med | ✓ |
| MRI/MRS (>= 7T) | ✓ |
| MRI/MRS (< 7T) | ✓ |
| micro-MRI/MRS (>= 7T) - ex-vivo | ✓ |
| micro-MRI/MRS (< 7T) - ex-vivo | ✓ |
| micro-CT - ex-vivo | ✓ |
| Image Analysis-bio * | ✓ |
Additional services offered by the Node
- Project planning and methodological setup
- Wet labs
- Cell culture facilities
- Animal housing
- Imaging probes
- Data processing and analysis
- Data storage
Instrument highlights
Unique aspects in Israel Bioimaging include high field MRI, correlative imaging across scales, advanced probe chemistry, advanced computation tools and unique applications such as marine imaging (Mediterranean and Red sea) and underwater imaging including deep water microscopy.
Contact details
Node head: Prof Michal Neeman michal.neeman@weizmann.ac.il
Office: Lili Kasumov lili.kasumov@weizmann.ac.il
Website is under construction
Weizmann Institute of Science: https://www.weizmann.ac.il
Tel Aviv University: https://english.tau.ac.il/
Technion: https://www.technion.ac.il/
Jerusalem: https://en.huji.ac.il/en
Ben Gurion University of the Negev: https://in.bgu.ac.il/en/pages/default.aspx
Bar Ilan University (BIU): https://www.biu.ac.il/en
BIU Light Microscopy Unit: http://lifefaculty.biu.ac.il/FacultyInstruments/index.php?option=com_content&view=article&id=42&Itemid=16
BIU Electron Microscopy Unit: https://nano.biu.ac.il/node/332
University of Haifa: https://www.haifa.ac.il/?lang=en&csrt=16680656402221511735